Part 8. Gout

Contents

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1. Preface To The American Edition Part 8. GoutThe following discussion is a brief résumé of a contribution on the pathogenesis and therapeutics of gout, which I published seven years ago in Section 8, Volume II, of the Wuerzburger Abhandlungen. C...
2. Note By The American Editor Part 8. GoutThe amount of literature that has been amassed in the last decade on the subject of gout presents a severe task to the clinician who desires to make himself familiar with the metabolism of this diseas...
3. I.-Differentiation Of GoutAn exhaustive treatise on our present knowledge of gout, the nature of its clinical manifestations and its treatment, cannot be confined to a short space; hence a brief exposition must forego amplific...
4. II. - Pathogenesis Of GoutPathological Chemistry of Uric Acid In so far as the chemistry of gout is considered, the main part of the discussion must be concerned with two conditions: - 1. The existence of a crystalline separa...
5. Uric Acid in the Blood- Pathogenesis Of GoutSince the method of Garrod gives no numerical values, we have employed for the determination of uric acid an iodine method which has lately been published by Ruhemann, and we have also used the iodine...
6. Causes of Sodium Urate Deposits- Pathogenesis Of GoutHis and Freudweiler have produced later evidence, that an inflammatory process, similar to the one we observe in gout, can be produced by a crystalline deposition of sodium biurate; and Kionka has sho...
7. Origin of Uric Acid - Pathogenesis Of GoutWhile uric acid was earlier regarded as an incomplete oxidation product of albumen, later researches, especially those of Possel and his pupil, have shown that uric acid in man and mammals is the end-...
8. Uric Acid Elimination - Pathogenesis Of GoutFor the excretion of the already formed uric acid from the blood and fluids of the tissues, there are two methods; 1. the excretion of uric acid as such through the kidneys. 2. the transformation of t...
9. Nephritis and Gout - Pathogenesis Of GoutThe number of cases of nephritis among gouty patients would be found much greater, even when no trace of albumen is discovered on clinical examination, if the existence of a latent chronic interstitia...
10. Endogenous Uric Acid - Pathogenesis Of GoutIn reference to the endogenous formation of uric acid in gout, we wish to cite an experiment which was carried out on a patient in the third medical clinic, who was suffering from gout in the joints o...
11. Uric Acid Retention - Pathogenesis Of GoutWhile we should not venture so far as to ascribe to uric acid retention the origin of every case of gout, we are not prepared to deny the possibility of such a process for many cases. At the same time...
12. Factors in the Precipitation of Urates - Pathogenesis Of GoutIn gout the overloading of the blood serum and the tissue fluid with uric acid, which has been the subject of so many discussions, is not, however, a necessary condition for the precipitation of the c...
13. III. Symptoms Of UricacidaemiaPain is not an invariable accompaniment of gout, the urate deposits being occasionally found without any history of a previous attack. Pain is felt if the process is very acute, or if the precipitated...
14. IV. Therapy Of Gout. Dietetics in GoutOn the ground that our present knowledge of the pathology of gout - in spite of the fact that we are still far from the goal - is not to be despised, these opinions are valuable in the treatment of go...
15. IV. Therapy Of Gout. Dietetics in Gout. ContinuedEXTRACTIVE SUBSTANCES IN VARIOUS MEATS 100 g. meat Extractive Average 100 g. meat Purins Average 1 Scraped beef 0.610 1 Scraped beef 0.071 2 Pike 0.601 2 Raw ham 0.05...
16. Beverages - Therapy Of GoutIn reference to beverages, a supply of fluid, copious rather than sparing, seems proper, care being observed, however, not to overtax the heart. It is preferable that the daily quantity of urine be tw...
17. Quantity of Food - Therapy Of GoutThe meals of the gouty subject should be small in bulk and low in nourishment. The stimulation of his appetite should be avoided in every way, and he should not use highly flavored sauces, or potted m...
18. Animal Compared with Vegetable Proteins - Therapy Of GoutThe mixture of various food materials should be also subject to the restrictions already mentioned; the quality of the resulting combination should be about normal. The amount of albumen (as free as p...
19. Water "Cures."The results of a medical treatment of a gouty diathesis are hard to control, because in a given individual the return of the attack of gout is very probable and frequent fluctuations are inevitable; a...
20. Drugs - Therapy Of GoutThe pharmacopoeia of gout has, in the last ten years, been remarkably enriched by the zeal of an energetic industry. Unfortunately this is more in the nature of a quantitative than a qualitative chara...
21. Treatment of Acute Attacks - Therapy Of GoutThe administration of colchicum or of the salicylic preparations is not, however, alone sufficient for the treatment of the attack; numerous general and local conditions require attention. If we know ...
22. Physical Methods - Therapy Of GoutThe principles of treatment employed in the first half of the attack seem to us very important, as then caution should dominate all proceedings; but the prescribed methods must not be continued too lo...
23. Hygiene - Therapy Of GoutIt is clear, without further explanation, that while we should seek to place at the disposal of our patients all of those factors which are available, either from common acceptance or personal experie...