Part 4. The Acid Autointoxications

Contents

The archive kept this book’s contents page but not its chapters. Each section is listed with the first lines it opened with.

1. Preface By The American Editor Part IV. The Acid AutointoxicationsProfessor von Noorden's studies into these derangements of metabolism which result in an overproduction of acid, thus endangering the proper degree of alkalinity of the blood, may seem at first more a...
2. I. General Remarks On Autointoxication With Acid Products Of MetabolismWithin recent years the idea has become firmly established in the minds of physicians that a variety of morbid phenomena are due to autointoxication - are, in other words, attributable to certain pois...
3. Acid Products of MetabolismOne form of autointoxication in particular, namely, intoxication by acid products of metabolism, in other words, acid intoxication, is well understood from the clinical point of view and is also well ...
4. How Acid Autointoxication OccursIn cases of perverted metabolism, an abnormal accumulation of acids can occur in two ways, namely, first, the excretion of acids may be reduced, or, second, the formation of acids may be increased, wh...
5. Acetonuria a Subdivision of Acid AutointoxicationThe clinical interpretation of these three bodies becomes very clear when we adhere to the view just enunciated, namely, that the appearance of the three acetone bodies is due to one common cause, i.e...
6. The Cause of Diabetic ComaHallervorden interpreted the increased excretion of ammonia in diabetes to signify the presence of some acid that was hitherto unknown. Later Stadelmann isolated crotonic acid from diabetic urine and ...
7. Lessened carbohydrate Feeding the Sole Cause of AcetonuriaAs against this view, Hirschfeld could show that the degree of acetonuria remained the same even if the caloric value of the food was brought up to the normal or above by the addition of fat, and that...
8. Ingestion of Butter may Increase AcetoneAnother phenomenon that demonstrates that acetonuria is largely dependent on the character of the food is the fact that the acetonuria varies with the amount and the character of the fat that is eaten...
9. II. The Sources Of The Acetone Bodies - The Acid AutointoxicationsWe have demonstrated so far that the excretion of acetone bodies in healthy subjects is dominated by the presence of certain quantities of carbohydrates in the food. We have also called attention to t...
10. Disproved Theories as to the Origin of the Acetone BodiesAt different times the carbohydrates, the pro teids and the fats have all been considered the mother substances of the acetone bodies. The old view that acetone is a product of the fermentation of car...
11. The Origin of B-oxybutyric AcidMore recently Sternberg has formulated the hypothesis that B-oxybutyric acid is formed from proteid via amidobutyric acid, and that the latter is a decomposition product of albumen. Feeding with this ...
12. III. Where Are The Acetone Bodies Formed? - The Acid AutointoxicationsAccording to the oldest views, acetone is formed in the intestinal tract from the decomposition of the carbohydrates. The so-called intestinal form of acetonuria and the fact that so-called acetone au...
13. IV. Pathological Non-Diabetic Acetonurias - The Acid AutointoxicationsIn the course of recent years, as already indicated, a number of so-called pathological acetonurias have been described that properly occupy an independent position. A number of causes have been incri...
14. Some Clinical forms of Acetonuria - The Acid AutointoxicationsWe will now discuss clinical acetonurias. The first of these is febrile acetonuria. Von Jacksch was the first to determine that considerable quantities of acetone, and at times of diacetic acid, are r...
15. Puerperal Eclampsia And The Eclampsia Of Pregnancy - The Acid AutointoxicationsHave also been attributed to autointoxication with acetone and the origin of the acetone has been laid in the intestine, according to Lorenz. Recently Stumpf and Stolz have gathered more casuistic mat...
16. V. Diabetic Acidosis - The Acid AutointoxicationsThe literature on the excretion of acetone in diabetes mellitus is enormous. There was much confusion in the beginning; but light was finally thrown upon this obscure subject when the factors determin...
17. Dangers in Dieting Diabetics too Strictly - The Acid Autointoxications1. Numerous diabetics living on a diet containing at least 60 to 80 grm. of carbohydrate and not passing any sugar on this diet, do not excrete more acetone than a healthy individual. As soon as such ...
18. Dangers in Dieting Diabetics too Strictly - The Acid Autointoxications. ContinuedThe patient O. K., age 55, suffered from diabetes that was recognized two months before his entrance into the hospital (Nov. 14th, 1902). On admission he excreted about 35 grm. of sugar and in additio...
19. The Effect of Fasting - The Acid AutointoxicationsA subject when fasting completely, possesses no residual carbohydrates after the fifth or sixth day (we know this from animal experiments and from a study of the respiratory quotient). The daily carbo...
20. The Acetonuria of Diabetes - The Acid AutointoxicationsThis shows that in diabetics acetonuria occupies a peculiar position, although on the other hand it is true that in many diabetics the same factors seem to influence the excretion of acetone as in hea...
21. VI. Therapeutic Considerations - The Acid AutointoxicationsIt may appear daring to speak of a special treatment of intoxication with the acetone bodies, inasmuch as this form of intoxication, according to our views, is no independent disease picture, but is m...
22. Von Noorden s Oatmeal Cure - The Acid AutointoxicationsThis treatment is carried out as follows: The patient for one or two weeks eats nothing but oatmeal gruel daily, 250 grm. of oat flour, 250 to 300 grm. of butter, 100 grm. of Roborat or of some other ...
23. The Administration of Alkalies - The Acid AutointoxicationsThe second means that we possess for combating acidosis is to disintoxicate the poisonous acids and to prevent their accumulation in the blood. Both these objects can be accomplished by the abundant a...
24. Treatment of Diabetic Coma - The Acid AutointoxicationsAlkali therapy has, of course, also been tried in coma itself. In this condition it is necessary to work quickly, and for this reason Naunyn has advised administering alkalies intravenously 35 to 40 g...